Category Archives: Hypertension

Association between Breastfeeding in reducing Hypertension risk

11Women who breastfeed more children, and intended for the long period, are less likely to suffer from hypertension once they reach menopause. This is not true of obese women, however. Elevated blood pressure is the most prominent risk factor for disease and death. Proof from epidemiologic data has too revealed the advantageous effects of breastfeeding on the healthiness of infants and their mothers. It has been reported that long-term breastfeeding is linked with reduced children’s allergies, celiac disease, obesity, and diabetes mellitus. Though, the effects of breastfeeding on maternal health have been not much studied compared with the effects on the children.

Numerous studies reliably found that lacking breastfeeding or early discontinuation was related with increased risks of diabetes mellitus, dyslipidemia, metabolic disorder, coronary heart disease, and cardiovascular diseases.

On the other hand few studies have recognized a clear relationship between breastfeeding and hypertension. The study population comprised 3,119 non-smoking postmenopausal women aged 50 years or older was taken under consideration. More children breastfed and the longer period of breastfeeding was associated with minor risk of hypertension in postmenopausal women, and level of obesity and insulin resistance directed the breastfeeding-hypertension correlation. In particular, the highest quintile of number of children breastfed (5 to 11) appeared a 51% lessen risk of hypertension compared by the lowest quintile (0 to 1). The highest quintile of the duration of breastfeeding (96 to 324 months) showed a 45% lower risk of hypertension.

Even though a broad variety of chronic diseases are not linked with breastfeeding, a few common mechanisms have been anticipated to lie behind the relationships between breastfeeding and these diseases. First, maternal metabolism (e.g., fat accumulation and insulin resistance) may be “reorganize” by breastfeeding subsequent to pregnancy, which diminishes the risk of obesity-related diseases. Second, oxytocin discharge stimulated by breastfeeding may be related to the decreased risk of these diseases.

#dyslipidemia #hypertension #Womenshealth # diabetes mellitus # coronary heart disease.

HYPERTENSION- Risk for people having fat concentration at abdominal area

4It is known that obesity is a risk factor for hypertension. Studies have also shown that several health issues like heart disease and cancer is due to the location of fat on a person’s body. However the relationship between site-specific accumulation of fat and hypertension is not clear.

For this purpose heart study was done for an average of 7 years with around 1000 patients to track development of hypertension. In this study systolic blood pressure of greater than or equal to 140, diastolic blood pressure of greater than or equal to 90 were considered. Imaging of patient’s visceral fat or fat located deep in the abdominal cavity like subcutaneous fat or visible fat over the body and lower body fat were also done.

Around 30% of patients developed hypertension near the end of the study. It was observed that higher Body Mass Index(BMI) were associated with increased incidence of hypertension. When abdominal fat content, lower-body fat content and overall fat content were observed, it was found that only abdominal fat remained independently associated with hypertension. Abdominal fat and hypertension relationship did not change with gender, age or race.

Visceral fat located behind the abdominal cavity and largely around the kidneys known as retroperitoneal fat were found to be strongly related with hypertension.

It could be suggested that presence of retroperitoneal fat are influencing the development of hypertension. This study could help in the prevention and management of hypertension.

High blood pressure more likely to affect pregnant women with hypertensive disorders

hypPregnant women diagnosed with hypertensive disorders are more susceptible to high blood pressure in the first year after delivery as compared to women who did not have any pregnancy-related hypertension.

Disorders like Hypertensive disorders are very common in pregnant women. Around 10 to 12% of all pregnant women are affected with this disorder and include  hypertension, preeclampsia and eclampsia.

According to various researches it is shown that hypertensive disorders during pregnancy is associated with long-term cardiovascular disease risk but very little is known about the effect of these conditions in the early years after delivery.

A study was done to see the importance to monitor and control blood pressure not only during pregnancy, but after delivery as well.

Researchers examined the electronic health records of around 6000 women who had prenatal care and delivered a baby. Women having pre-pregnancy high blood pressure were not included in the analysis.

In the study it was found that women who had a hypertensive disorder during pregnancy were 2.5 times more likely to develop pre-hypertension or hypertension in the year after delivery and women with pre-eclampsia were 2.7 times more likely to to develop pre-hypertension or hypertension in the year after delivery than those women who maintained a normal blood pressure during their pregnancy, after controlling for differences between the groups.

It was observed that the women with pregnancy-related hypertension were be slightly younger and overweight or obese before pregnancy in comparison to women with normal blood pressure during pregnancy

So, it is advised that Women who develop hypertension, preeclampsia, or eclampsia in pregnancy must discuss about monitoring their blood pressure after delivery with their physicians

Also further research should be done to determine early blood pressure screening and to improve treatment of women with pregnancy-related hypertensive disorders so that cardiovascular disease can be prevented.

Steroid Hormone Imbalance Leading to Treatment-Resistant Hypertension

Heart2019Studies carried by Researchers of London, found that the steroid hormone ‘aldosterone’ makes salt amass in the circulation system. The salt aggregation happens even in patients on sensible eating methodologies, and pushes up pulse regardless of utilization of diuretics and other standard medications.

Two patients in the examination with already resistant hypertension could fall off all medications after a benign aldosterone-causing nodule formation in one adrenal and surgically removed after medical procedure.

Hypertension standouts amongst the most widely recognized and imperative preventable reasons for heart diseases, heart disappointment, stroke and sudden passing. It influences more than 1 billion individuals over the world and records for around 10 million possibly avoidable death for every year.

Most patients can be dealt with successfully with changes in accordance with their way of life and the utilization of consistent prescription. In any case, in upwards of 1 of every 10 patients, circulatory strain can be hard to control and is named ‘resistant hypertension’. These patients are at the most astounding danger of stroke and coronary illness in light of the fact that their circulatory strain stays uncontrolled.

There has been an awesome story of utilizing refined current techniques to tackle an old issue – why a few patients have clearly recalcitrant hypertension. The revelation of salt over-burden as the basic reason has empowered us to distinguish the hormone which drives this, and to treat or fix the greater part of the patients.

These outcomes are vital on the grounds that they will change clinical practice over the world and will help enhance the circulatory strain and results of our patients with resistant hypertension.

It is noteworthy when such a large number of advances in prescription rely upon costly advancement, that we have possessed the capacity to return to the utilization of medications created over 50 years prior and demonstrate that for this hard to-treat populace of patients, they work extremely well.

In past work, the group demonstrated that resistant hypertension is controlled much better by the medication spironolactone (a steroid blocker of aldosterone) than by drugs authorized for use in hypertension. Presently they have demonstrated that the prevalence of spironolactone is expected over its capacity to beat the salt overabundance in resistant hypertension.

They likewise found that spironolactone can be substituted, to great impact, by a medication, amiloride, which could be a possibility for patients unfit to endure spironolactone.

The examination originates from the PATHWAY-2 contemplate, some portion of a progression of concentrates intended to grow more powerful methods for treating hypertension. It explored the theory that resistant hypertension was fundamentally caused by an imperfection in taking out salt and water and that the hypertension in these patients would be best treated by extra diuretic treatment to advance salt and water discharge by the kidneys.