Category Archives: Endocrinology

Diabetes and Frozen Shoulder

Among the numerous complications frequently connected with diabetes, one of the foremost mystifying and painful is the frozen shoulder. Adhesive capsulitis, the condition’s biological term, is a pathological condition of the shoulder joint which causes the painful and gradual loss of motion.

The connective tissue of the shoulder joint inflames and stiffens, causing chronic pain, limiting mobility and disturbing sleep. The associated pain varies between sharp stings that radiate through the bicep to dull ache.

Link between diabetes and frozen shoulder:

There’s no conclusive connect link between the shoulder condition and the disease. Few studies indicate frozen shoulder is caused by glycosylation of the collagen in the shoulder joint.

Metabolic Diseases Img

What Happens to the Shoulder?

Adhesive capsulitis is characterized by three stages, in spite of the fact that the severity and length of the stages may vary from individuals to individuals.

  • Stage One: Freezing – The most painful stage of the condition. During this stage, there’s a slow onset of pain coinciding with a progressive reduction in the range of motion (ROM) of the shoulder. Even simple movements like behind the back or reaching above the head are accompanied by tremendous pain and cramping.
  • Stage Two: Frozen- There’s a slow reduction of pain during this stage, but stiffness remains.
  • Stage Three: Thawing- During this final stage, there’s a gradual enhancement in ROM, as well as a lessening of stiffness and pain.


Frozen shoulder sees a wide extend of treatments. Diagnosis for the condition involves a physical exam, MRI, and x-ray, which is best for distinguishing soft tissue issues. Once diagnosed, physicians can advise an assortment of approaches, including physical therapy, surgical manipulation, steroid injections, and even supervised neglect.

Physical therapy is the foremost treatment for frozen shoulder. Therapists devise a particular exercise and stretching regimen to address the limited motion, restricted rotation, pain and strength. The regimen frequently utilizes heat and can take few weeks or even months for recognizable improvement.

Frozen shoulder proceeds to confuse health experts, and, surprisingly, there’s no way to prevent it. Early detection and proper treatment can allow a patient with diabetes to avoid the most painful and consequences of the condition.


Endocrine-disrupting chemicals may be debilitating fertility

1Endocrine system:

The most work of endocrine organs is to discharge hormones specifically into the circulation system. Hormones are chemical substances that influence the movement of another portion of the body (target location). In substance, hormones serve as couriers, controlling and planning exercises all through the body.

Eventually, hormones control the work of whole organs, influencing such different forms as development and improvement, propagation, and sexual characteristics. Hormones too impact the way the body employments and stores vitality and control the volume of liquid and the levels of salts and sugar (glucose) within the blood. Exceptionally little sums of hormones can trigger very huge reactions within the body.2

Potential EDCs are for the foremost portion man-made, found in various materials such as pesticides, metals, included substances or contaminants in nourishment, and individual care things. EDCs have been suspected to be related with adjusted regenerative work in individuals and females; opened up rehash of breast cancer, unordinary movement plans and neurodevelopmental delays in children, as well as changes in secure work.

In this way, diethylstilbestrol (DES) a non-steroidal estrogen, which is respected as a verification of concept, actuates clear cell carcinoma among youthful ladies. EDCS may be found in plastic bottles and metal nourishment cans (BPA), restorative gadgets (phthalates), cleansers, fire retardants (polybrominated diphenyl ethers), nourishment (BPA), toys (phthalates), beauty care products and drugs (parabens), and pesticides (alkyl phenols such as nonylphenol). The pernicious impacts of endocrine disruptors constitute a genuine open wellbeing issue. Be that as it may concerning the components of activity of EDCs, numerous questions stay unanswered and require assist examinations.3

Human presentation to EDCs happens by means of ingestion of nourishment, tidy and water, by means of inward breath of gasses and particles within the discus, and through the skin. EDCs can too be exchanged from the pregnant lady to the creating embryo or child through the placenta and breast drain. Pregnant mothers and children are the foremost helpless populaces to be influenced by formative exposures, and the impact of exposures to EDCs may not end up apparent until afterward in life. Inquire about too appears that it may increment the helplessness to non-communicable infections. Number of variables related to fertility, and one of the most conclusions of their consider was that destitute semen quality contributed to increments in infertility and the utilize of helped regenerative innovation. Numerous of the male regenerative issues can be due to harm to the testicles amid embryonic advancement. Whereas the regenerative issues seem emerge from hereditary changes.

Chemicals are a fundamental component of our day by day lives. But a few chemicals, known as endocrine disruptors, can have destructive impacts on the body’s endocrine (hormone) framework. Hormones act in exceptionally little sums and at exact minutes in time to direct the body’s advancement, development, propagation, digestion system, insusceptibility and behaviour. Endocrine disruptors meddled with normal hormone frameworks, and the wellbeing impacts can be felt long after the presentation has halted. Presentation to endocrine disruptors can have life-long impacts and can indeed have results for the next era.