Cannabis has been using as a mind-altering drug from the Prehistoric times. Even today, it is a popular recreational drug around the world, only behind tobacco, alcohol, and caffeine. It is commonly known as Marijuana and is the most commonly used illicit drug in youth all over the world.
It is known that the psychoactive effects of Cannabis have three phases:
- Primary psychoactive effect- relaxed state of euphoria because of the compound, tetrahydrocannabinol.
- Secondary psychoactive effect- introspection, higher-order thinking, the philosophical thinking among the cases of anxiety and paranoia.
- Tertiary psychoactive effect- increased heart rate and hunger, due to the chemical compound 11-OH-THC, the metabolite of THC produced in the liver.
It is found that the use of cannabis by adolescent results in hypomanic episodes (elevated mood) and sleep deprivation which are usually considered as symptoms of bipolar disorder and it greatly affects the daily life. Many more concerns such as memory and cognition problems and schizophrenia have been observed in young people.
The researchers analyzed data from the Avon Longitudinal Study of Parents and Children found that the use of cannabis during the teenage results in the hypomanic symptoms in the later years.
With the frequent use of Cannabis, Cannabinoid receptors (CB1) are distributed throughout the brain and gets active in neurotransmitter release and concentrations across the nervous system. It alters the genetic expression of neural development and endocannabinoid system leading to a series of neurochemical and neurostructural aberrations which results in poorer emotional outcomes and hypomania in adulthood.
Cannabis use in youthful individuals is common and related to psychiatric disorders. Be that as it may, the imminent interfaces between cannabis use and bipolar disorder side effects have rarely been investigated.”
Cannabis is one of the foremost commonly utilized unlawful substances of abuse in western countries. Problematic utilize within the common population is as high as 9.5% within the United States, whereas 2.6% of the UK population report having been cannabis subordinate within the last year.